The Pan African Journal of Emergency Medicine and Critical Care is proud to present Volume 3, Issue 1 (2025), a compelling collection of research and case studies that address critical issues in emergency medicine and critical care across resource-limited settings, with a particular focus on Ethiopia and the broader African context. This issue features a diverse range of manuscripts that highlight both clinical and systemic challenges, offering insights into patient safety, toxicology, trauma, infectious diseases, and critical care practices.

Key manuscripts in this issue include:

Acute phenolbarbital poisoning in a resource-limited setting: This study explores the clinical presentation, management, and outcomes of phenolbarbital poisoning, emphasizing the challenges faced in low-resource environments.

Acute Intentional Iron Overdose in Pregnancy: An Overview of Case and Treatment in a Resource Setting: This case study examines the complexities of managing iron overdose in pregnant women, offering guidance for clinicians in similar settings.

Road Traffic Injury (RTI) Epidemic is on the Rise, Not Declining in Ethiopia: A Systematic Review and Meta-Analysis: A comprehensive review of the growing RTI crisis in Ethiopia calls for urgent public health interventions.

Atypical Guillain-Barré Syndrome with Bulbar Dysfunction and Descending Paralysis: A rare case presentation that expands the understanding of atypical manifestations of Guillain-Barré syndrome.

Clinical Pattern, Management Outcome, and Associated Factors of Patients Admitted to the COVID-19 ICU Center of St. Paul's Hospital Millennium Medical College: This study provides critical insights into the management and outcomes of COVID-19 patients in an intensive care setting.

Documentation Practice and Associated Factors Among Nurses Working in Adult Intensive Care Units at Public Hospitals in Addis Ababa, Ethiopia, 2022: Highlighting the importance of accurate documentation, this research identifies barriers and facilitators to effective record-keeping in ICUs.

This issue underscores the journal’s commitment to advancing emergency medicine and critical care in Africa by addressing pressing clinical challenges, sharing best practices, and advocating for systemic improvements. The manuscripts collectively contribute to the growing body of knowledge aimed at improving patient outcomes and healthcare delivery in resource-limited settings.

We invite researchers, clinicians, and policymakers to engage with this issue, as it offers valuable perspectives and evidence-based recommendations for addressing some of the most critical issues in emergency and critical care medicine today.